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Vitamin B-12, also known as cobalamin, is a vital nutrient crucial for various bodily functions like red blood cell formation, neurological health, and DNA synthesis

haptocorrin) and passes into the duodenum where the R protein is removed by pancreatic proteases and free cobalamin binds to R protein (IF)

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In pernicious anaemia, the immune system mistakenly attacks the gastric parietal cells that produce intrinsic factor, leading to B12 deficiency over time

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