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Conclusion Clinical trial data from large, controlled studies demonstrate the efficacy and safety of GLP-1 agonists in terms of A1C reduction, beneficial effects on body weight, and a low risk for hypoglycemic events when used as monotherapy

Semaglutides effects on weight loss, inflammation, and pain The semaglutide group also experienced an average 10.5% decrease in body weight compared to only an average 2% decrease in the placebo group

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Consider seeking referral to a specialist if you experience persistent pain despite first-line therapy, infertility after 6-12 months of attempting conception (earlier if age 35), abnormal imaging findings (such as endometriomas), or recurrent emergency department visits

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