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People who saw the best results usually describe modest but steady weight loss in the 8 to 15 pound range over six months, paired with smaller portion sizes and reduced food noise
This mechanism matters for b12 absorption
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Long-term treatment with Wegovy may be necessary to maintain weight loss results
10.1038/s41597-025-05325-w Sci
A 2025 study found that tripling semaglutides dose to 7.2 mg led to roughly 19% weight loss over 72 weeks, compared to 16% at the standard dose, a meaningful gain, though with higher rates of side effects
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