Semaglutide and cardiovascular outcomes in obesity without diabetes (SELECT trial)
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Mann JFE, Orsted DD, Brown-Frandsen K, Marso SP, Poulter NR, Rasmussen S, et al
Hypotonic may cause hemolysis if administered intravenously without adequate solute. This reiterates that the product is only for diluting drugs , and reminds healthcare providers to ensure the final mixture is safe for infusion
The most frequently reported treatment-emergent adverse events included nausea, diarrhea and vomiting, most of them reported as mild or moderate and occurred during the dose titration period
The method of administration and dosage are key factors that will directly affect the outcome