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These observations should be interpreted with caution and warrant confirmation in further larger, adequately powered trials, specifically designed to address this question, ideally through targeted analyses of regulators of sulfur and NO pathways in pathological pregnancies with IPTB

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The discrepancy between, on the one hand, repeated findings of an association between indices of relative vitamin B12 deficiency and cognitive impairment and, on the other hand, the lack of substantial benefit in therapeutic trials of B vitamin supplementation is not understood

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Glutathione may reduce chemotherapy efficacy, particularly with platinum or alkylating agents