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Importantly, its secretagogue action is selective, having no effect on stress hormones like cortisol, an overpresence of which can cancel your efforts to gain muscle or shed fat.7 8 Why are CJC-1295 and ipamorelin used together

Chen, J., Yin, D., & Dou, K

Pharmacokinetic Rationale for Co-Administration The timing of injection matters because the two peptides operate on different pharmacokinetic timescales

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Using C2C12 mouse myoblasts, the study confirmed that the MGF E-domain peptide increases myoblast proliferation while inhibiting terminal differentiation and critically, that this effect was maintained in the presence of a neutralising anti-IGF-1R antibody directly establishing that MGF E-peptide signals via an IGF-1R-independent mechanism

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