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study documented significantly accelerated tendon-to-bone healing in rat rotator cuff models compared to untreated controls, with VEGF pathway upregulation as a proposed mechanism [1]
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Eli Lilly is also studying the orforglipron pill on adults with Type 2 diabetes with the company announcing back in April that the medication could help reduce hemoglobin A1C levels a blood test that shows average blood sugar levels over two to three months in addition to helping people lose weight
Weight LossEffective, But Not Universal - Up to ~47% of patients can achieve 15% weight loss - But response variesmany patients do not reach clinically meaningful thresholds - Compared to bariatric surgery, pharmacotherapy still has limitations Importantly, weight loss is largely fat-mass driven, with relative preservation of lean massif supported by proper nutrition and resistance training
It took decades for sports nutrition to realize that a short-distance sprinter or a power athlete has different nutritional needs than a long-duration endurance athlete
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