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betaine TMG is, among other things, a critical component of cellular energy metabolism, especially as a methyl donor within mitochondria.46 In a study on trained college athletes, a daily 5g dose of TMG improved power and maximal strength in various lifts.29 Another study, using a smaller 2.5mg daily dose, found improvements in exercise performance and a reduction in post-exercise cortisol levels in the treatment group.12 It has even been shown to improve anaerobic power, oxygen utilization, and sprint performance after two weeks of taking just 2g/day.47 Beta-alanine A position statement by the International Society of Sports Nutrition supports the use of beta-alanine for improving exercise performance and attenuating neuromuscular fatigue.34 However, these findings relate to a 4-6g daily dose, while most pre-workout supplements contain a bit less

There is compelling evidence from preclinical studies that l-carnitine and ALCAR can improve energy status, decrease oxidative stress and prevent subsequent cell death in models of adult, neonatal and pediatric brain injury

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Benefits of B12 are extensive: from mood and nerve health to cardiovascular, eye, skin, and liver health