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Answer a few key questions to begin understanding your biology and what you can do about it

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The biggest difference between Ozempic and Tirzepatide is the receptor each targets

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In mice in which the GLP-1R gene has been knocked out the anorectic responses to injected OXM are abolished

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Going forward, practice the pinching technique and ensure you're inserting into the subcutaneous fat layer, not muscle

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The semaglutide and tirzepatide trials changed that expectation: Semaglutide 2.4 mg once weekly produced average weight loss around 15% at ~68 weeks in adults without diabetes, with a substantial fraction of participants losing 1520% of baseline weight

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