For example, a study published in October 2023 found that the use of GLP-1 drugs for weight loss was associated with an increased risk for pancreatitis, gastroparesis, and bowel obstruction
Furthermore, in human reviews 3 of muscle protein metabolism, activation of IGF-1/Akt/mTOR signaling directly correlated with higher protein synthesis rates and improved muscle density, particularly in response to resistance training and nutrient intake
These injectables are a new class of medication that is being used for weight loss
The breadth of its action is its greatest strength here
The metabolite, 1-kestose is considered a fructo-oligosaccharide (i.e., a prebiotic compound), that cannot be hydrolyzed by the gastrointestinal track and is fermented by hydrolytic microbes in the gut 94,95
Authors included Rozalina G