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While previous generations GLP-1 agonists (liraglutide) have led to weight loss of 5-10% in most cases, semaglutide can lead to weight loss of up to 20%

In 2025, Ozempic costs about $900 each month if you take 2 mg

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Since chronic hyperglycemia imposes deleterious effects on -cell function by building up glucose toxicity [26], ameliorating glucose toxicity with intensive insulin therapy may restore -cell function [27,28] and improve -cell incretin sensitivity through a similar mechanism

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