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The amino acid sequence of IGF-1 LR3 is MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA

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That research is on a specific prescription formulation rather than Aqualyx itself, so it is fair to say the class is well studied even though Aqualyx is mostly backed by real-world clinical use

Circ Res 2001

Martin, B., Lopez de Maturana, R., Brenneman, R., Walent, T., Mattson, M