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Intramuscular (IM) Injections IM injections deliver medication deeper into the muscle, where it can be absorbed into the bloodstream more quickly

The best absorbed administration is through IV or through nebulizing (breathing it in)

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The exact mechanisms arent fully understood, but they could involve reducing inflammation in the brain, improving insulin sensitivity (which has been linked to depression), and influencing neurotransmitter systems that regulate mood

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doi:10.7759/cureus.34723 OBrien PE, Hindle A, Brennan L, et al