Building on its GLP-1/GIP dual agonist CT-388, Roche is pursuing a future combination strategy with the amylin analogue petrelintide
Although the percentage of patients using statins did not differ significantly between the two groups, the percentage tended to be lower in ALT responders than in ALT non-responders
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If SEM was not reported directly, it was calculated from the confidence interval where available, or otherwise from the standard deviation and the sample size
Some worry these drugs bypass deeper issues
The practical significance of these interactions is debated and depends heavily on formulation, concentration, and pH