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doi: 10.1016/j.seizure.2022.11.007 61 IkomaYSasakiDMatsuiK

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Protective role of glutathione in the hippocampus after brain ischemia

Special Precautions Administration of high doses of the oral formulations of levocarnitine for long periods of time is not recommended in patients with severely compromised renal function or in ESRD patients on dialysis due to the fact that major metabolites formed following oral administration trimethylamine (TMA) and trimethylamine-N-oxide (TMAO) will accumulate since they can not be efficiently removed by the kidneys

A comprehensive meta-analysis of 37 randomized controlled trials involving 2,292 participants found that L-Carnitine supplementation significantly decreased body weight by 1.21 kg, body mass index (BMI) by 0.24 kg/m, and fat mass by 2.08 kg compared to placebo

Chen, L., Mai, B., & Luo, X