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Gastrointestinal adverse effects of GLP-1 agonistsincluding nausea, vomiting, and dehydrationcould be exacerbated by alcohol use and may complicate medication adherence

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doi: 10.1691/ph.2018.8650 26 DuX

found that PBT434, a novel compound with moderate iron affinity, can protect the survival of SNpc neurons, improve nigrostriatal connectivity and motor function in mice, without disrupting normal iron homeostasis (229)

Why the off phase matters: continuous dosing flattens pituitary response over time

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