At her heaviest, the 5ft 1in woman weighed 220lbs (100kg)
Fatigue may result from multiple factors including significant caloric deficit from appetite suppression, metabolic adaptation to weight loss, nutritional deficiencies, gastrointestinal side effects affecting food and fluid intake, and changes in blood glucose levels
Endoscopy, where the procedure is performed entirely through the mouth and esophagus, is indicated in a small subset of patients and typically leads to durable weight loss similar to that of gastric bypass
The use of ultrasound to evaluate stomach contents just before surgery is also recommended, particularly for those with severe symptoms
Future work will shed light on these aspects
Additionally, a notable decline in calcium salt mineralisation was evident in the si-LRP5 group (Figure 5A)