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Falta de respuesta adecuada : Si despus de 3-6 meses de tratamiento a la dosis teraputica completa no se observan mejoras significativas en el control glucmico (reduccin de HbA1c de al menos 0.5-1%) o en el peso corporal (prdida de al menos 5% del peso inicial cuando se prescribe para manejo de peso), debe consultar con su mdico
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Mechanistic studies need to be performed to understand what drives GLP-1R upregulation and the increase in pro-tumorigenic transcription
Nature 535 , 444447 (2016)
These interviews have been lightly edited for clarity
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