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Poor respiration and fatalities were not observed (Duplancic et al., 2014)

While IGF-1 has important physiological functions, elevated levels carry potential concerns including increased cell proliferation that may support tumor growth in individuals with cancer or pre-cancerous conditions, accelerated aging processes through growth pathway activation, potential cardiovascular effects with chronic elevation, and metabolic consequences including effects on glucose and lipid metabolism

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Healthy red blood cell formation

Lipidated or PEGylated peptides often dissolve slowly and may need longer incubation or a small organic cosolvent