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Synergistic amplification has been documented
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It is synthesized in every cell from the amino acids glutamate, cysteine, and glycine (Lu, Biochimica et Biophysica Acta , 2013)
More significant side effects are rare but possible
Losartan at doses of 1 mg/kg (Group VII), 3 mg/kg (Group VIII), and 10 mg/kg (Groups III, V, IX, and X) was injected intraperitoneally twice, at 1 and 12 h after the acetaminophen injection
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