A More Useful Decision Frame If youre choosing sermorelin or ipamorelin primarily for fatigue, recovery, or body composition, consider that these symptoms often come from more common issues (sleep disorders, thyroid disease, iron deficiency, overtraining, depression/anxiety, medication effects)
Moreover, continuous supplementation is frequently necessary to maintain effects
We are going to improve insulin resistance
Pancreatitis: As with all GLP-1 receptor agonists, there is a theoretical risk of acute pancreatitis
Dec 2015;133(12):1415-1424
Third, many GLP-1 users were already borderline deficient before starting therapy, since obesity itself is associated with lower vitamin D levels due to sequestration in adipose tissue