Realistic timeline expectations: Patients who expect visible muscle changes within 2 to 3 weeks are typically disappointed
It activates the wound healing cascade by promoting angiogenesis and accelerating the migration of repair cells to the treatment site
In contrast, substitution to an amidated proline instead of an amidated tyrosine in the C-terminus of rAmy is well tolerated, resulting in enhanced affinity and activity at both the CTR and AMYRs, but, in some cases, reduced selectivity between these receptors 18
This incongruent response suggested that these endogenous protective systems may also be a target of GAs and contributing to PAN (123)
for more details, see Sampson et al., 2021 13
Our goal was to create a vaccine that mirrored the drugs natural structure