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86 MoriguchiS.TakamiyaA.NodaY.HoritaN.WadaM.TsugawaS.et al (2019)

These often focus on digestive comfort, muscle maintenance, and micronutrient balance rather than additional blood sugar lowering, which helps avoid the risks associated with berberine

Undesirable side effects are based on their mechanism of action: renal failure, arterial hypotension, urinary tract candidiasis, body weight reduction and hyperkalemia.80 Dapagliflozin is the SGLT2 inhibitor with the most clinical data available to date

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This amphiphilic character influences solubility behaviour and chromatographic retention