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The FDA is expected to issue its decision by no later than March 2026
After the supplementation, the glycine levels increased by 117.6% and the cysteine by 55.1%
However, these side effects do subside over time
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In 2,339 participants at the 12mg dose, the safety profile was consistent with TRIUMPH-4 and GLP-1 class expectations with one important improvement: discontinuation due to side effects dropped to 11.3% , compared to 18.2% in TRIUMPH-4's osteoarthritis population
High protein intake is especially important because it provides the greatest satiety per calorie, partially compensating for the loss of GLP-1 mediated appetite suppression
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