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Key findings from the Phase 2 trial included: Dose-dependent reductions in body weight across all active treatment arms Significant improvements in waist circumference, a key marker of visceral adiposity Reductions in fasting insulin levels and HbA1c Improvements in lipid profiles, including triglycerides Phase 3 trials are currently ongoing and are expected to include larger, more diverse populations with more granular subgroup analyses, including sex-specific data

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The researchers found that among adults who were overweight or obese who completed the 20-week run-in period with subcutaneous semaglutide, maintaining treatment with semaglutide resulted in continued weight loss over the following 48 weeks compared to switching to placebo

They leave out the edge cases