Gene mapping studies have identified lipid peroxidation, mitochondrial dysfunction, and impaired neurogenesis as potential factors contributing to the neuronal phenotype and cognitive impairment in DS
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Oxidative stress and accelerated aging are the clearest targets, since glutathione is the front-line molecule that neutralizes free radicals before they damage mitochondria and DNA
High costs limits options The list price for Ozempic and Mounjaro each run more than $1,000 a month, which can be difficult to afford, even for people with private insurance, depending on the required copay
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