Individually, these steps may seem modest
Although these data suggest that GSH depletion per se, at least for a short period of time, is not sufficient to cause cell injury, a prolonged depletion of mucosal GSH leads to severe degeneration of intestinal mucosal epithelial cells, as shown in BSO-treated mice (Martensson et al, 1990)
Theoretical concerns exist with anticoagulants, blood pressure medications, and immunosuppressants
Both ingredients offer unique benefits, and they actually work well together
Generally a separation of 24 or more hours of any antioxidant IV (GSH, Nutrient IV followed by GSH etc.) allows plenty of time to have both the oxidative and anti-oxidative therapies work to maximum
Future studies are warranted to identify the mechanism underlying this dual inhibition as well as potential targets for treating pathological conditions associated with both necroptosis and ferroptosis