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Furthermore, obesity contributes to myocardial dysfunction and apoptotic injury through excessive accumulation of metabolites, including triglycerides and free fatty acids, a process termed cardiac lipotoxicity [44, 48, 49]
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10.1016/S2213-8587(21)00179-0 60 NicholsG
at the time of the study, in the Netherlands, GLP-1RAs were restricted to reimbursement in people with a BMI 30 kg/m 2 with inadequate glycaemic control on metformin and a sulphonylurea, and in people with a BMI 30 kg/m 2 with inadequate glycaemic control on basal insulin for more than 3 months [37]
Eur J Prev Cardiol 26(2_suppl):2532
