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This partial reversal may be driven by factors such as compliance challenges, waning drug efficacy or measurement limitations

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On the other hand, there is now unanimous consensus for stages III and IV that only ART is effective (6)

Patients who are also taking SGLT2 inhibitors (e.g., dapagliflozin, empagliflozin) for type 2 diabetes or heart failure should be aware that these medicines carry additional risks of dehydration and diabetic ketoacidosis in the peri-operative period

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Companies with these practices face lower regulatory risk