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Many people find themselves stuck on long waiting lists just to see their GP, and then face further delays for blood tests

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Natural GLP-1 supplements such as Fitty GLP-1 Daily can be used alongside fasting if cleared by a healthcare professional

Notably, MQC dysfunction can further amplify the SASP response: impaired mitochondrial autophagy leads to continuous activation of the NF-B pathway by damaged mitochondria, promoting the secretion of IL-6, TNF- and other SASP factors, which not only maintain the senescent state of chondrocytes in an autocrine manner, but also induce senescence of surrounding normal chondrocytes in a paracrine manner, expanding the pathological damage (62)

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