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Research is needed to confirm these findings and optimize treatment strategies for this vulnerable population.

These dendritic branches might be the primary receivers of GLP-1 signaling, as GLP-1 fibers are denser around the central canal, and GLP-1 also appears to be transmitted via the CSF 55

Women should discontinue tirzepatide at least one month before planned conception and seek immediate medical advice if pregnancy occurs during treatment

In short, the answer is yes, but there is more to consider beyond GLP-1

6.5.3.2 Safety and tolerability Across the PIONEER program, the safety and tolerability of oral semaglutide were generally consistent with the known profile of GLP-1RAs

Is it normal to not lose weight the first few weeks on tirzepatide