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doi: 10.1038/nutd.2013.20 76 WeiMHuangFZhaoLZhangYYangWWangSet al
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From the genetics angle, there are some pediatric, congenital causes of 5-oxoprolinuria which not surprisingly involved defects in enzymes of the gamma-glutamyl cycle (in particular, mutations in glutathione synthetase and 5-oxoprolinase have been identified in these patients).
PNAS, 2010
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