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Studies show sustained weight loss maintenance and cardiovascular benefits even during plateau periods, and many patients achieve cumulative weight loss of 1522% over 2+ years with appropriate dose adjustments

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Clinical trials involving investigational medicinal products (CTIMPs) in the UK are governed by the Medicines for Human Use (Clinical Trials) Regulations 2004 (as amended), with safety reporting requirements set out in MHRA and Health Research Authority (HRA) guidance

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