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Why this protects the heart and possibly more By reducing visceral fat and correcting the insulin-resistant environment that created it, GLP-1 therapies improve the biology that drives cardiovascular disease

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GIP Receptor Activity GIP is another incretin hormone that may contribute to glucose homeostasis and nutrient metabolism

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The synthesis of TMAO and crotonobetaine is strongly reduced by the administration of antibiotics, thus demonstrating that the intestinal microbiota plays an essential role in their synthesis