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& Krimberg, R
The analysis reveals the limited nature of available evidence, which consists primarily of case reports, retrospective chart review, and other small observational studies
Severe dehydration can lead to acute kidney injury, a recognized risk with GLP-1 receptor agonists in the setting of volume depletion, as noted in FDA prescribing information
Starting at the lower end of dosing ranges (20-30 mcg) and assessing response before increasing is advisable
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