Stephens FB, Wall BT, Marimuthu K, Shannon CE, Constantin-Teodosiu D, Macdonald IA, Greenhaff PL
Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity
doi:10.1056/NEJMoa1603827 Marso SP, Bain SC, Consoli A, et al
So it is not a measurement of how long benzyl alcohol stays effective
Exenatide formulations show variable nausea rates: the twice-daily immediate-release preparation (Byetta) tends to produce higher rates of nausea (approximately 3050%), whilst the once-weekly extended-release formulation (Bydureon) demonstrates improved tolerability with nausea rates of approximately 1424%, according to their respective SmPCs
The administration of linezolid was found to impair mitochondrial function, intensify oxidative stress, and activate inflammatory pathways, resulting in notable biochemical and histopathological alterations