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After vortexing and centrifuging at 14,000 g for 10 min at 4 C, the supernatant was collected for targeted metabolomics analysis

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A 2018 Sports Medicine review (Fielding et al.) suggested L-Carnitine supplementation may moderately reduce muscle damage, fatigue, and enhance exercise capacity and post-exercise recovery

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Effectiveness of different benfotiamine dosage regimens in the treatment of painful diabetic neuropathy

Acknowledgements The authors thank the research resource division (RRD) (RIKEN Center for Brain Science) and RIKEN CBS-EVIDENT Open Collaboration Center (RIKEN Center for Brain Science) for technical assistance, Yukiko Nagai (RIKEN Center for Brain Science) for secretarial work, Kenichi Nagata (Nagoya University) and members of the Laboratory for Proteolytic Neuroscience (RIKEN Center for Brain Science) for beneficial suggestions