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Can athletes get a Therapeutic Use Exemption (TUE) for MOTS-c
The semaglutide component follows the same dose escalation schedule as standard compounded semaglutide: Weeks 1-4: 0.25 mg semaglutide (0.1 mL) Weeks 5-8: 0.5 mg semaglutide (0.2 mL) Weeks 9-12: 1.0 mg semaglutide (0.4 mL) Weeks 13-16: 1.7 mg semaglutide (0.68 mL) Week 17+: 2.4 mg semaglutide (0.96 mL) The niacinamide dose scales proportionally with the injection volume
Semaglutide, a generic equivalent to Ozempic and Wegovy, was FDA-approved in 2021 for chronic weight management
Monitor urine colorpale yellow indicates proper hydration
Semaglutide Dosing Schedule and Weight Loss Outcomes Clinical evidence from the STEP trials showed that participants receiving 2.4 mg of semaglutide weekly lost an average of 15% of their body weight over 68 weeks, compared to less than 3% in the placebo group
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