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133 Similarly, mice lacking ZIP3 exhibit decreased CD4 + CD8 + double-positive (DP) thymocytes but increased CD4 + and CD8 + single-positive thymocytes, indicating its role in regulating T cell development

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Prior studies have demonstrated that bariatric surgery in people with MS can lead to significant weight reduction without worsening neurologic disability or ambulation outcomes, while also improving vitamin D levels, a factor previously associated with lower relapse risk and reduced MRI lesion activity

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