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Phase 2 trial (NEJM 2023) randomized 338 adults with obesity to retatrutide doses from 1 mg to 12 mg/week
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Researchers should distinguish database records, analytical-method papers, structural studies, and model-specific literature from batch-specific documentation for the RUO material being procured
This triple-agonist approach, targeting GLP-1, GIP, and glucagon receptors, produced the most dramatic weight loss results seen in any Phase 2 obesity trial
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