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Appetite fluctuation during the transition period deserves special attention
However, not everyone experiences immediate or consistent weight loss while on these medications, which can be perplexing and frustrating
Potential explanations include: Allergic or hypersensitivity reactions : Rarely, patients may develop urticaria (hives), angioedema, or pruritus as part of an immune response to semaglutide or excipients in the formulation
& Cornelis, S
The observational findings corroborate earlier SELECT trial results but do not establish causation, making further prospective research essential
The SmPC advises using non-oral contraception or adding a barrier method for 4 weeks after starting tirzepatide and after each dose increase
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