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Method of Literature Search PubMed and the Cochrane Library were searched in April 2021 (Figure 1)
Semaglutide is a glucagon-like peptide-1 receptor agonist (GLP1-RA) that is administered subcutaneously once weekly
Adequate planning is required for patients of reproductive age
Ladenheim EE
But the addition of glucagon receptor agonism overwhelms the GIP benefit
Semaglutide remains the right call if you have established cardiovascular disease (SELECT data), chronic kidney disease with T2D, or MASH with an FDA indication today
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