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The kidney-protective effects of GLP1-RAs are believed to result from reductions in inflammation and oxidative stress, in part through direct binding to glucagon-like peptide 1 (GLP1) receptors present on kidney glomerular and tubular cells [51]

Pernicious Anemia : This is an autoimmune disorder in which the body's immune system attacks and destroys the cells that produce intrinsic factors, leading to vitamin B12 deficiency

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What I found in reviewing the data is that most gastrointestinal side effects peaked during dose escalation and reduced once participants reached their maintenance dose

GLP-1 is a gut hormone that stimulates insulin secretion after eating, which promotes a feeling of fullness, helps to regulate blood sugar, and reduces hunger cravings