Preclinical work, predominantly from Sikiric and colleagues, has examined its activity in gastrointestinal ulcer models, tendon and ligament repair models, and endothelial/VEGF (vascular endothelial growth factor)-linked angiogenesis pathways
Human clinical trials are limited, and more data is needed to fully understand safety, efficacy, and optimal protocols
Following a Cellulaze treatment, you may experience some soreness, but you will be able to return to your normal activities in a day or two
Weekly Metrics Worth Tracking Pain at rest (NRS 0 to 10), recorded at the same time each day (morning before activity works well) Pain with the most provocative exercise movement for that injury Range of motion at the affected joint, measured with a goniometer or a reliable phone app Functional milestones: for example, single-leg heel raise repetitions for Achilles tendinopathy, or overhead press weight for shoulder pathology When to Contact Your Prescriber Contact your prescriber if pain acutely worsens after a period of improvement, if you develop swelling or heat at the injury site suggesting possible infection (particularly if you are injecting locally), or if you notice any new and unexplained neurological symptoms such as numbness, tingling, or weakness in a limb
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Liver and visceral fat also decreased significantly [4]