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Gastrointestinal surgery significantly increases risk, particularly procedures involving the stomach (gastrectomy) or terminal ileum resection, as these remove or bypass critical absorption sites

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Thats because vitamin B12 is bound to protein and can only be released by digestive substances in the stomach (hydrochloric acid and gastric protease) to be absorbed

Because peptides typically break down quickly in the digestive tract, most are administered through injections

It's one of the most well-researched brightening ingredients in modern skincare

Most patients experience only 24-48 hours of downtime