The AWARD-7 trial, which was the first clinical trial among moderate-to-severe CKD and T2DM displayed convincing protective effects on eGFR after treatment with GLP-1RAs [46]
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Oxidative Medicine and Cellular Longevity, 2011 , 194586
It Adds Context to IGF-1 Levels IGF-1 tells us how much anabolic/growth signal is in circulation
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It also points to the need for better strategies to make these treatments more accessible and available to those who need them. Prior to this research, a small study of 106 postmenopausal women published in 2024 in the medical journal Menopause found that those who were on both MHT and the GLP-1 drug semaglutide had lost about 16 percent of their total body weight after a year, compared to 12 percent for women on a GLP-1 alone