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Until recently, when basal insulin alone was not enough to maintain glycemic control, the main effective intensification option was to add mealtime bolus insulin in the main meal
This process proceeded until participants had tried all three supplements ( 6 )
While semaglutide activates only the GLP-1 receptor, tirzepatide is a dual GIP and GLP-1 receptor agonist
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An investigational lab-made peptide (research code LY3437943) from Eli Lilly, now in Phase 3 trials
