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In GPX4 knockout mice, the incidence and mortality in spontaneous AKI increased significantly 76
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In contrast, TIGAR overexpression or treatment with Fer-1, a ferroptosis inhibitor, significantly increases NADPH, GPX4, and GSH levels, reduces GSSG expression, and attenuates neuronal ferroptosis and neurological impairment
This gives you six doses of 2.5 mg or three doses of 5 mg from a single vial
Roh JL, Kim EH, Jang H, Shin D
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