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Safety, Side Effects, and Tolerability When Combining Medications Metformin is generally well tolerated but commonly causes transient gastrointestinal upsetnausea, diarrhea, or metallic tastein the first 12 weeks

The semaglutide variant for weight management, Wegovy, raked in $3.32 billion, while sales of the oral type 2 diabetes version of the drug, Rybelsus, hit $2.72 billion

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