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b-d , HCC-1806 cells were grown in control media or cystine-free (n = 8 technical replicates from 2 independent experiments

Key Point: L-Carnitine helps transport fat for energy use, but fat burning still requires physical activity and energy demand

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Portal and peri-portal inflammation and hepatocellular necrosis with infiltrating lymphocytes, plasma cells and eosinophils have been reported in 5 cases treated by ipilimumab with severe hepatic toxicity [33]